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Men have higher mortality. [8] SLE significantly increases the risk of cardiovascular disease, with this being the most common cause of death. [5] While women with lupus have higher risk pregnancies, most are successful. [1] Rate of SLE varies between countries from 20 to 70 per 100,000. [2] Young women are affected about nine times more often ...
Photosensitivity is a known symptom of lupus, but its relationship to and influence on other aspects of the disease remain to be defined. [4] Causes of photosensitivity may include: change in autoantibody location; cytotoxicity; induction of apoptosis with autoantigens in apoptotic blebs; upregulation of adhesion molecules and cytokines
Tumid lupus erythematosus is a rare, but distinctive entity in which patients present with edematous erythematous plaque. [ 2 ] Lupus erythematosus tumidus (LET) was reported by Henri Gougerot and Burnier R. in 1930.
Women are far more likely than men to get autoimmune diseases, when an out-of-whack immune system attacks their own bodies — and new research may finally explain why. ... More than 24 million ...
Researchers at Northwestern Medicine and Brigham and Women’s Hospital say they’ve discovered a root cause of lupus, a disease that affects hundreds of thousands of people in the U.S.
Osteonecrosis is also associated with cancer, lupus, sickle cell disease, [11] HIV infection, Gaucher's disease, and Caisson disease (dysbaric osteonecrosis). [1] [12] Bisphosphonates are associated with osteonecrosis of the mandible (jawbone). [13] The condition may also occur without any clear reason. [1]
CAR-T immune therapies were developed to fight cancer. The same technique just showed promise treating lupus, but it costs hundreds of thousands. 6 lupus patients effectively cured by a cancer ...
Women appear to generally mount larger inflammatory responses than men when their immune systems are triggered, increasing the risk of autoimmunity. Involvement of sex steroids is indicated by that many autoimmune diseases tend to fluctuate in accordance with hormonal changes, for example: during pregnancy, in the menstrual cycle, or when using ...