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A wide variety of alkaloid and non-alkaloid compounds have been identified in various species of ephedra.Of the six ephedrine-type ingredients found in ephedra (at concentrations of 0.02-3.4%), the most common are ephedrine and pseudoephedrine, [12] which are the sources of its stimulant and thermogenic effects. [3]
A 2015 systematic review found that pseudoephedrine lacked performance-enhancing effects at therapeutic doses (60–120 mg) but significantly enhanced athletic performance at supratherapeutic doses (≥180 mg). [19]
Essentially, pseudoephedrine occurs naturally along with other ephedrine-related compounds in certain plants. However, the pseudoephedrine found in most pharmaceutical products is not derived from plant matter, but instead is produced by yeast fermentation of dextrose in the presence of the enzyme pyruvate decarboxylase.
As of June 28, 2024 all provinces and territories require single-ingredient ephedrine and pseudoephedrine products in retail settings to be sold behind the counter in pharmacies, and by pharmacists (or, in some cases, also by individuals working under the supervision of a pharmacist, such as pharmacy technicians), to prevent their misuse and ...
Because it contains pseudoephedrine, its purchase in the United States was severely restricted by the Combat Methamphetamine Epidemic Act of 2005 over fears that any product containing pseudoephedrine can be used to make methamphetamine. [1]
A decades-old cosmetic procedure called mesotherapy, which involves injecting unregulated mixtures of vitamins and drugs under the skin to reduce under-eye bags, is regaining popularity in the US.
Ephedra was used 5000 years ago in China as a medicinal plant; its active ingredients are alkaloids ephedrine, pseudoephedrine, norephedrine (phenylpropanolamine) and norpseudoephedrine . Natives of Yemen and Ethiopia have a long tradition of chewing khat leaves to achieve a stimulating effect.
A judge told the parents of 27-year-old Ellen Greenberg, a Philadelphia teacher found dead with 20 stab wounds in 2011, that the city's declaration of suicide was "puzzling."
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780 Old Hickory Blvd, Brentwood, TN · Directions · (615) 238-0127