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  2. Signs and symptoms of Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    A possible explanation for the mental symptoms of sub-clinical thyroid disease, might be found in the fact that the brain has among the highest expression of THR's [clarification needed], and that neurons are often more sensitive than other tissues to thyroid abnormalities, including sub-clinical hyperthyroidism and thyrotoxicosis.

  3. Hashimoto's thyroiditis - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_thyroiditis

    TSH is the preferred initial test of thyroid function as it has a higher sensitivity to changes in thyroid status than free T 4. [ 64 ] Biotin can cause this test to read "falsely low". [ 21 ]

  4. Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Graves'_disease

    Thyroid-associated ophthalmopathy (TAO), or thyroid eye disease (TED), is the most common extrathyroidal manifestation of Graves' disease. It is a form of idiopathic lymphocytic orbital inflammation , and although its pathogenesis is not completely understood, autoimmune activation of orbital fibroblasts , which in TAO express the TSH receptor ...

  5. Thyrotroph Thyroid Hormone Sensitivity Index - Wikipedia

    en.wikipedia.org/wiki/Thyrotroph_Thyroid_Hormone...

    The Thyrotroph Thyroid Hormone Sensitivity Index (abbreviated TTSI, also referred to as Thyrotroph T4 Resistance Index or TT4RI) is a calculated structure parameter of thyroid homeostasis. It was originally developed to deliver a method for fast screening for resistance to thyroid hormone .

  6. Thyroid disease - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease

    Thyroid disease is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to regulate energy use ...

  7. Thyroid Feedback Quantile-based Index - Wikipedia

    en.wikipedia.org/wiki/Thyroid_Feedback_Quantile...

    The Thyroid Feedback Quantile-based Index (TFQI) is a calculated parameter for thyrotropic pituitary function. It was defined to be more robust to distorted data than established markers including Jostel's TSH index (JTI) and the thyrotroph thyroid hormone sensitivity index (TTSI).

  8. Thyroid hormone resistance - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormone_resistance

    The syndrome can present with variable symptoms, even between members of the same family harboring the same mutation. [1] Typically most or all tissues are resistant to thyroid hormone, so despite raised measures of serum thyroid hormone the individual may appear euthyroid (have no symptoms of over- or underactivity of the thyroid gland).

  9. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Short overview of thyroid homeostasis. [1]The hypothalamic–pituitary–thyroid axis (HPT axis for short, a.k.a. thyroid homeostasis or thyrotropic feedback control) is part of the neuroendocrine system responsible for the regulation of metabolism and also responds to stress.

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