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Under the free margin of the nail, hyperkeratosis causes the nail plate to pull up and results in a deformity that resembles a gaping toecap separated from the sole at the seam. Pitting and sporadic cross-ridging of the nail plate are more common in fingernails than toenails.
The defining characteristic of a keratoacanthoma is that it is dome-shaped, symmetrical, surrounded by a smooth wall of inflamed skin, and capped with keratin scales and debris. It grows rapidly, reaching a large size within days or weeks, and if untreated for months will almost always starve itself of nourishment, necrose (die), slough, and ...
The use of podiatry drills, in the absence of engineering controls and personal protective equipment, is an occupational hazard to the healthcare provider.Nail dust collected during foot care procedures performed in office settings has been found to contain keratin, keratin hydrolysates, microbial debris, and viable fungal elements, including dermatophytes (most commonly Trichophyton rubrum ...
Early actinic keratosis with parakeratosis, with black arrows indicating one of multiple retained nuclei in the stratum corneum. Parakeratosis is a mode of keratinization characterized by the retention of nuclei in the stratum corneum. [1]
Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis, or skin), often associated with the presence of an abnormal quantity of keratin, [1] and is usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed ...
Pachyonychia congenita (often abbreviated as "PC") is a rare group of autosomal dominant skin disorders that are caused by a mutation in one of five different keratin genes. Pachyonychia congenita is often associated with thickened toenails, plantar keratoderma, and plantar pain.
Onycholysis is a common medical condition characterized by the painless detachment of the nail from the nail bed, usually starting at the tip and/or sides. [1] On the hands, it occurs particularly on the ring finger but can occur on any of the fingernails.
Other symptoms include itch, painful fissures, strong body odor, and absence of sweat. [6] Symptoms vary in severity and extent of skin involvement. [5] The two main types are divided into one involving palms and soles and the other without. [6] EI is caused by a genetic mutation. [6] The condition involves the clumping of keratin filaments. [5 ...