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Some examples of antihistamines with their indications and routes of administration Class of antihistamines Examples Uses Route of administration First generation Diphenhydramine, Chlorpheniramine, Brompheniramine, Promethazine: Allergic rhinitis, allergic conjunctivitis, atopic dermatitis, urticaria, itching Oral, topical, intraocular
Antihistamines can be very effective in controlling the symptoms of urticaria and are usually the first choice of treatment. There are two types of antihistamines: first-generation, such as diphenhydramine, which can cause drowsiness, and second-generation, such as cetirizine and loratadine, which are less likely to cause drowsiness.
Ebastine is a second-generation H1 receptor antagonist that is indicated mainly for allergic rhinitis and chronic idiopathic urticaria. [5] It is available in 10 and 20 mg tablets [6] and as fast-dissolving tablets, [7] as well as in pediatric syrup. It has a recommended flexible daily dose of 10 or 20 mg, depending on disease severity.
Hives, or urticaria, are itchy pink welts that could appear anywhere on your skin. Some are bumps as small as a pinhead, while others may merge together to cover large patches of your skin.
Bilastine is an antihistamine medication used to treat hives (), allergic rhinitis and itchy inflamed eyes (allergic conjunctivitis) caused by an allergy. [6] It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H 1 receptor, preventing these allergic reactions. [7]
Urticaria; Angioedema; Diarrhea; Pruritus (atopic dermatitis, insect bites) Anaphylactic or anaphylactoid reactions—adjunct only; Nausea and vomiting; Sedation (first-generation H 1-antihistamines) H 1-antihistamines can be administered topically (through the skin, nose, or eyes) or systemically, based on the nature of the allergic condition.
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