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Drug-induced lupus erythematosus is an autoimmune disorder caused by chronic use of certain drugs. These drugs cause an autoimmune response (the body attacks its own cells) producing symptoms similar to those of systemic lupus erythematosus (SLE). There are 38 known medications to cause DIL but there are three that report the highest number of ...
A value of greater than 1.5 units relative to a control serum is considered a positive ELISA test for the anti-histone antibodies. Patients with drug-induced lupus erythematosus typically have positive tests for anti-histone antibodies but do not have indications for anti-dsDNA antibodies. Patients with idiopathic systemic lupus erythematosus ...
Thus, one or more of the following tests are generally performed to detect lupus anticoagulant if a high suspicion remains, and/or specify lupus anticoagulant as the cause of an abnormal mixing test: Phospholipid-sensitive functional clotting testing, such as the dilute Russell's viper venom time, Kaolin clotting time, or silica clotting time. [13]
Scientists at Northwestern Medicine may have discovered the cause of lupus. Here's what to know about the breakthrough and what it means for lupus treatments.
The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...
Drug-induced lupus erythematosus is a (generally) reversible condition that usually occurs in people being treated for a long-term illness. Drug-induced lupus mimics SLE. However, symptoms of drug-induced lupus generally disappear once the medication that triggered the episode is stopped.
The drug is being tested in patients with the most common form of lupus, systemic lupus erythematosus, where the patient's immune system attacks the body's own tissues and potentially leads to ...
In a review of 65 individuals with cSLE caused by the drugs cited in the above section "Drug", discontinuing the responsible drug in 100% of cases and treatment with a glucocorticoid in 53.3% of cases, hydroxychloroquine in 8.4% of cases, and cyclophosphamide in 3.3% of cases resulted in improvements in 92.0% of the 63 individuals available for ...