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A substance of very high concern (SVHC) is a chemical substance (or part of a group of chemical substances) which has been proposed as a candidate for inclusion on the Authorization or Restriction list (see: ECHA Lists) of REACH. [1]
The SIN List is composed of chemicals evaluated by the environmental NGO ChemSec as meeting EU criteria for being Substances of Very High Concern (SVHCs) under Article 57 of REACH, being either carcinogenic, mutagenic or reprotoxic (CMR), persistent, bioaccumulative and toxic (PBT), very persistent and very bioaccumulative (vPvB), or posing an equivalent environmental or health threat., [1] [2]
Supply of substances to the European market which have not been pre-registered or registered is illegal (known in REACH as "no data, no market"). REACH also addresses the continued use of chemical substances of very high concern (SVHC) because of their potential negative impacts on human health or the environment. From 1 June 2011, the European ...
When listed in Annex XIV of the REACh regulation, a substance is therefore assigned a “sunset date” after which its use will be banned, unless an Authorisation is granted for a definite period of time. As of today (2022/03/02), 223 substances are listed on the Candidate List [6] and 54 substances (date 2022/03/02) are listed in the Annex ...
This is the list of extremely hazardous substances defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. § 11002). The list can be found as an appendix to 40 CFR 355. [1] Updates as of 2006 can be seen on the Federal Register, 71 FR 47121 (August 16, 2006). [2]
Formerly on Proposition 65 list Substance CAS Registry Number † Date removed Bisphenol A (BPA) 80-05-7 April 11, 2013 Allyl chloride: 107-05-1 October 29, 1999 Phenyl glycidyl ether: 122-60-1 April 4, 2014 α-Methyl styrene: 98-83-9 April 4, 2014 tert-Amyl methyl ether: 994-05-8 December 13, 2013 n-Butyl glycidyl ether: 2426-08-6 April 4, 2014
The drug or other substance has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug or other substance under medical supervision. The complete list of Schedule I substances is as follows. [1] The Administrative Controlled Substances Code Number for each substance is included.
[13] However, in the European Union, D 5 was characterized as a substance of very high concern (SVHC) due to its PBT and vPvB properties and was thus included in the candidate list for authorisation. [14]