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Insulin glargine sold under the brand name Lantus among others is a long-acting modified form of medical insulin, used in the management of type 1 and type 2 diabetes. [7] It is injected just under the skin. [7]
Insulin glargine-yfgn is interchangeable and less expensive than the reference product, insulin glargine (Lantus), which had been approved in 2000. [104] The FDA requires that new insulin products are not inferior to existing insulin products with respect to reduction in hemoglobin A1c.
The onset of action of subcutaneous insulin glargine is somewhat slower than NPH human insulin. It is clear solution as there is no zinc in formula. [9] [better source needed] The biosimilar insulin glargine-yfgn (Semglee) was approved for medical use in the United States in July 2021, [10] and in the European Union in March 2018. [11]
Mylan Pharmaceuticals recalled one batch of Insulin Glargine Injection, 100 units/mL (U-100), 3 mL prefilled pens, which are sold in cartons of five. ... but unbranded Insulin Glargine-yfgn pens ...
A 2011 Cochrane review showed a HbA1c reduction of 0.20% more with Exenatide 2 mg compared to insulin glargine, exenatide 10 μg twice daily, sitagliptin and pioglitazone. [27] Exenatide, together with liraglutide, led to greater weight loss than glucagon-like peptide analogues. [27]
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Insulin glargine/lixisenatide, sold under the brand name Soliqua among others, is a fixed-dose combination medication that combines insulin glargine and lixisenatide and is used to treat diabetes. The most common side effects include hypoglycemia (low blood glucose), diarrhea, vomiting and nausea (feeling sick).
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