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Severe cutaneous adverse reactions (SCARs) are a group of potentially lethal adverse drug reactions that involve the skin and mucous membranes of various body openings such as the eyes, ears, and inside the nose, mouth, and lips. In more severe cases, SCARs also involves serious damage to internal organs. SCARs includes five syndromes:
PVA usually has an underlying cause, attributed to existing skin diseases and disorders associated with a cutaneous lymphoma or inflammation. [5] Mycosis fungoides is the common lymphoma believed to cause PVA, although it may be considered a precursor when the lymphoma is occult (hidden) and undiagnosed. [ 5 ]
Acute graft-versus-host-disease Vacuolar alteration of various severity, from focal or diffuse vacuolation of the basal keratinocytes (grade I), to separation at the dermoepidermal junction (grade III) Involvement of the hair follicle [2] Rarely eosinophils [2] Allergic drug reaction Rarely involvement of hair follicles. [2] Frequently ...
Chickenpox, is a highly contagious skin disease caused by the varicella-zoster virus (VZV). [33] It is characterized by pruritic blister-like rash which may cover entire body, affecting all age groups. [33] [34] Rates of chickenpox are higher in countries which lack adequate immunization programs. In 2014, it has been estimated that global ...
The genetic skin disorders collectively known as epidermolysis bullosa display skin fragility and a tendency to develop chronic, non-healing wounds. [12] Comorbid ailments that may contribute to the formation of chronic wounds include vasculitis (an inflammation of blood vessels), immune suppression , pyoderma gangrenosum , and diseases that ...
Lichen sclerosus (LS) is a chronic, inflammatory skin disease, of unknown cause, which can affect any body part of any person, but has a strong preference for the genitals (penis, vulva), and is also known as balanitis xerotica obliterans when it affects the penis. Lichen sclerosus is not contagious.
While emotional stress may make the symptoms worse, it is not a cause. [2] The disorder is not contagious. [2] A diagnosis is typically based on the signs, symptoms and family history. [3] Treatment involves avoiding things that make the condition worse, enhancing the skin barrier through skin care and treating the underlying skin inflammation.
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]