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Ellis–Van Creveld syndrome often is the result of founder effects in isolated human populations, such as the Amish and some small island inhabitants. Although relatively rare, this disorder does occur with higher incidence within founder-effect populations due to lack of genetic variability.
In a study from 2016, important differences in the children's innate immune cells and in the allergy inducing nature of the dust in their homes were found, leading to the conclusion that the Amish environment had protected against asthma by shaping the innate immune response. [14] Most Amish clearly seem to use some form of birth control, a ...
The Amish have few written explanations why certain things are regulated by the Ordnung. Non-Amish are not allowed to attend their council meetings, and most Amish are hesitant to discuss the details with outsiders, therefore the precise reasons are difficult to explain. They formulate their rules with two interconnected goals in mind.
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Salt and pepper developmental regression syndrome, also known as Amish infantile epileptic syndrome [4] or GM3 deficiency syndrome, [5] is a rare autosomal recessive progressive neurological disorder characterized by developmental delay, severe intellectual disability, seizures, and skin pigmentation irregularities.
“For most Amish teenagers, Rumspringa is a time to explore Amish life without being considered under the rule of their parents. Because remember, family and hierarchy are extremely important.”
Engraving of an escaped slave, published in 1837. Cartwright described the disorder—which, he said, was "unknown to our medical authorities, although its diagnostic symptom, the absconding from service, is well known to our planters and overseers" [9] —in a paper delivered before the Medical Association of Louisiana [7]: 291 that was widely reprinted.
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