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Drusen, from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a few small ("hard") drusen is normal with advancing age, and most people over 40 have some hard drusen. [1]
In children, optic disc drusen are usually buried and undetectable by fundoscopy except for a mild or moderate elevation of the optic disc. With age, the overlying axons become atrophied and the drusen become exposed and more visible. They may become apparent with an ophthalmoscope and some visual field loss at the end of adolescence. [7]
Choroidal nevus with drusen can be considered as a sign of chronicity since drusen take years to develop and appear. [14] Drusen are composed of lipids and can actually be an indicator that a tumour is a benign nevus as opposed to a cancerous melanoma. [15] In nevi imaged by OCT, about 41% are found to have drusen. [16]
Early childhood is a stage of rapid growth, development and learning and each child makes progress at different speeds and rates. [13] It is essential to integrate physical training designed in accordance with the anatomical characteristics andage-related characteristics of a child's development, to ensure the normal physical development of ...
ECCE begins at birth and can be organized in a variety of non-formal, formal and informal modalities, such as parenting education, health-based mother and child intervention, care institutions, child-to-child programs, home-based or center-based [Child care|childcare], kindergartens and pre-schools. The whole goal of ECCE programs is to prepare ...
When a child is constipated, it means that the child has fewer than two bowel movements (BMs) a week; has stools that are hard and dry, or are lumps; has stools that are difficult or painful to ...
The History of early childhood care and education (ECCE) refers to the development of care and education of children between birth and eight years old throughout history. . ECCE has a global scope, and caring for and educating young children has always been an integral part of human societi
While the problem is more intractable in developing countries, the developed world still does not equitably provide quality early childhood care and education services for all its children. In many European countries, children, mostly from low-income and immigrant families, do not have access to good quality early childhood care and education.