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  2. Lifileucel - Wikipedia

    en.wikipedia.org/wiki/Lifileucel

    The US Food and Drug Administration (FDA) approved Lifileucel through the accelerated approval pathway and granted the application orphan drug, regenerative medicine advanced therapy, fast track, and priority review designations under the brand name Amtagvi to Iovance Biotherapeutics. [3]

  3. Duvelisib - Wikipedia

    en.wikipedia.org/wiki/Duvelisib

    Duvelisib is a Phosphoinositide 3-kinase inhibitor, specifically of the delta and gamma isoforms of PI3K. [9] This class of compounds works by preventing PI3K from playing its role in transducing signals from outside of cells into various intracellular pathways involved in cell cycle regulation, apoptosis, DNA repair, senescence, angiogenesis and cell metabolism, including the PI3K/AKT/mTOR ...

  4. Decitabine/cedazuridine - Wikipedia

    en.wikipedia.org/wiki/Decitabine/cedazuridine

    Decitabine/cedazuridine was approved for medical use in the United States and Canada in July 2020, [7] [8] [9] [12] and in the European Union in September 2023. [6]The U.S. Food and Drug Administration (FDA) granted the application of decitabine combined with cedazuridine priority review and orphan drug designation.

  5. US FDA approves Amgen drug for small cell lung cancer - AOL

    www.aol.com/news/us-fda-approves-amgen-drug...

    The U.S. Food and Drug Administration on Thursday granted accelerated approval to Amgen's tarlatamab, a targeted immunotherapy for adults in the advanced stages of hard-to-treat small cell lung ...

  6. Tarlatamab - Wikipedia

    en.wikipedia.org/wiki/Tarlatamab

    Tarlatamab, sold under the brand name Imdelltra, is an anti-cancer medication used for the treatment of extensive-stage small cell lung cancer. [2] It is a bispecific T-cell engager that binds delta-like ligand 3 and CD3.

  7. Vorasidenib - Wikipedia

    en.wikipedia.org/wiki/Vorasidenib

    Vorasidenib was approved for medical use in the United States in August 2024. [5] [6] It is the first approval by the US Food and Drug Administration (FDA) of a systemic therapy for people with grade 2 astrocytoma or oligodendroglioma with a susceptible isocitrate dehydrogenase-1 or isocitrate dehydrogenase-2 mutation. [5]

  8. Enasidenib - Wikipedia

    en.wikipedia.org/wiki/Enasidenib

    Enasidenib, sold under the brand name Idhifa, is an anti-cancer medication used to treat relapsed or refractory acute myeloid leukemia. [2] [3] It is an inhibitor of isocitrate dehydrogenase 2 (IDH2). [2] Common side effects of enasidenib include nausea, vomiting, diarrhea, increased levels of bilirubin (substance found in bile), and decreased ...

  9. Zanidatamab - Wikipedia

    en.wikipedia.org/wiki/Zanidatamab

    Zanidatamab, sold under the brand name Ziihera, is a humanized monoclonal antibody used for the treatment of HER2-positive biliary tract cancer. [1] [2] It is an IgG-like bispecific HER2-directed antibody.

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