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When taken in prescribed quantities, codeine-promethazine is quite safe, [16] but dangers arise in higher doses since promethazine is a depressant of the central nervous system (CNS), and codeine is a respiratory depressant. When codeine is taken in very large amounts, it can cause one to stop breathing. [16]
Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold [ 4 ] and may also be used for sedating people who are agitated or anxious, an effect that has led to ...
Due to dextromethorphan's selective serotonin reuptake inhibitor-like action, the sudden cessation of recreational dosing in tolerant individuals can result in mental and physical withdrawal symptoms similar to the withdrawal from SSRIs. These withdrawal effects can manifest as psychological effects, including depression, irritability, cravings ...
Symptoms are most likely to occur when you stop taking an antidepressant cold turkey (which, by the way, isn’t advised)—or in cases where you’re in the process of tapering off. Discontinuing ...
But when you stop taking the drugs, the weight can come back. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ways to reach us. Mail. Sign in ...
PPIs, which include heartburn drugs such as Prilosec, Nexium and Prevacid, are one of the best-selling classes of drugs in the world.
Many prescription and legal nonprescription substances can also cause withdrawal symptoms when individuals stop consuming them, even if they were taken as directed by a physician. The route of administration, whether intravenous , intramuscular , oral , or otherwise can also play a role in determining the severity of withdrawal symptoms.
The land opens up to scrubby, snow-covered prairie and barbed-wire fence stretching for miles. Here, Fischer says, even a beautiful day can feel desolate. At the first rest stop, their usual one, a flyer pinned to the bulletin board outside the unheated bathrooms lists suicide hotline numbers: “If you are depressed please Avoid drugs and alcohol.