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Microtiter plates with 96, 384 and 1536 wells. A microplate, also known as a microtiter plate, microwell plate or multiwell, [1] is a flat plate with multiple "wells" used as small test tubes. The microplate has become a standard tool in analytical research and clinical diagnostic testing laboratories.
[28] [29] ELISA can also be used in toxicology as a rapid presumptive screen for certain classes of drugs. Enzyme-linked immunosorbent assay plate. The ELISA was the first screening test widely used for HIV because of its high sensitivity. In an ELISA, a person's serum is diluted 400 times and applied to a plate to which HIV antigens are attached.
These plates are often grouped with an adjacent principal plate on a tectonic plate world map. For purposes of this list, a microplate is any plate with an area less than 1 million km 2 . Some models identify more minor plates within current orogens (events that lead to a large structural deformation of Earth's lithosphere ) like the Apulian ...
Plate readers, also known as microplate readers or microplate photometers, are instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. They are widely used in research, drug discovery , [ 1 ] bioassay validation, quality control and manufacturing processes in the pharmaceutical and ...
ELISA plate showing various cortisol levels. Enzymes used in ELISAs include horseradish peroxidase (HRP), alkaline phosphatase (AP) or glucose oxidase. These enzymes allow for detection often because they produce an observable color change in the presence of certain reagents.
A gel plate is cut to form a series of holes ("wells") in an agar or agarose gel. A sample extract of interest (for example human cells harvested from tonsil tissue) is placed in one well, sera or purified antibodies are placed in another well and the plate left for 48 hours to develop.
A multiplex assay is a derivative of an ELISA using beads for binding the capture antibody. Multiplex assays are still more common in research than in clinical settings. [2] In a multiplex assay, microspheres of designated colors are coated with antibodies of defined binding specificities.
Map of the Cocos–Nazca spreading centre. Abbreviations used: GMP Galápagos microplate, GSC Galápagos spreading centre, GT Galápagos transform, IT Inca transform, EFZ Ecuador fracture zone, PFZ Panama fracture zone, MAT Middle America Trench, ER Ecuador Rise, CRR Costa Rica Rise
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