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The Golgi apparatus (/ ˈ ɡ ɒ l dʒ i /), also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. [1] Part of the endomembrane system in the cytoplasm , it packages proteins into membrane-bound vesicles inside the cell before the vesicles are sent to their destination.
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. [ 6 ]
Conserved oligomeric Golgi complex subunit 2 is a protein that in humans is encoded by the COG2 gene. [5] [6]Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification.
Golgin subfamily A member 4 is a protein that in humans is encoded by the GOLGA4 gene. [5] [6]The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs).
20340 Ensembl ENSG00000090863 ENSMUSG00000003316 UniProt Q92896 Q61543 RefSeq (mRNA) NM_001145666 NM_001145667 NM_012201 NM_009149 NM_001368315 RefSeq (protein) NP_001139138 NP_001139139 NP_036333 NP_033175 NP_001355244 Location (UCSC) Chr 16: 74.45 – 74.61 Mb Chr 8: 111.88 – 111.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Golgi apparatus protein 1 is a protein that in ...
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes protein synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus.
Golgin subfamily A member 3 is a protein that in humans is encoded by the GOLGA3 gene. [5] [6] [7]The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs).
Giantin or Golgin subfamily B member 1 is a protein that in humans is encoded by the GOLGB1 gene. [5] [6] [7] Giantin is located at the cis-medial rims of the Golgi apparatus and is part of the Golgi matrix that is responsible for membrane trafficking in secretory pathway of proteins.