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That is, the molar mass of a chemical compound expressed in g/mol or kg/kmol is numerically equal to its average molecular mass expressed in Da. For example, the average mass of one molecule of water is about 18.0153 Da, and the mass of one mole of water is about 18.0153 g.
Immunoglobulin G (IgG) is a type of ... IgG is the main type of antibody found in blood and extracellular fluid, ... has a total molecular weight of about 150 kDa. [7]
The Damköhler numbers (Da) are dimensionless numbers used in chemical engineering to relate the chemical reaction timescale (reaction rate) to the transport phenomena rate occurring in a system. It is named after German chemist Gerhard Damköhler , who worked in chemical engineering, thermodynamics, and fluid dynamics. [ 1 ]
They are usually artificial peptides or proteins with a molar mass of about 3 to 20 kDa. (Antibodies are ~150 kDa.) (Antibodies are ~150 kDa.) Nucleic acids and small molecules are sometimes considered antibody mimetics as well, but not artificial antibodies, antibody fragments and fusion proteins composed from these.
The tetanus toxin protein has a molecular weight of 150 kDa.It is translated from the tetX gene as one protein which is subsequently cleaved into two parts: a 100 kDa heavy or B-chain and a 50 kDa light or A-chain.
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A monoclonal antibody, for comparison, is 150 kDa, and a single-domain antibody, the smallest type of antigen-binding antibody fragment, 12–15 kDa. Affibody molecules have been shown to withstand high temperatures (90 °C (194 °F)) or acidic and alkaline conditions ( pH 2.5 or pH 11, respectively).