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  2. Modified-release dosage - Wikipedia

    en.wikipedia.org/wiki/Modified-release_dosage

    Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1] Sustained-release dosage forms are dosage ...

  3. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    [citation needed] A dose of 40 mg of aspirin a day is able to inhibit a large proportion of maximum thromboxane A 2 release provoked acutely, with the prostaglandin I2 synthesis being little affected; however, higher doses of aspirin are required to attain further inhibition. [15]

  4. Aspirin - Wikipedia

    en.wikipedia.org/wiki/Aspirin

    Aspirin-modified COX-2 ... Tablets, typically of about 75–100 mg and 300–320 mg of immediate-release aspirin (IR-ASA). Dispersible tablets. Enteric-coated tablets.

  5. Daily low-dose aspirin has its benefits — and risks. Here's ...

    www.aol.com/lifestyle/aspirin-every-day-why-not...

    For years, doctors recommended that older adults at a higher risk for heart attack or stroke take a low-dose aspirin once a day to lower their risk.

  6. Liberation (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Liberation_(pharmacology)

    This can mean that the same dose of a drug in different forms can have different bioequivalence, as they yield different plasma concentrations and therefore have different therapeutic effects. Dosage forms with modified release (such as delayed or extended release) allow this difference to be usefully applied.

  7. Pharmaceutical formulation - Wikipedia

    en.wikipedia.org/wiki/Pharmaceutical_formulation

    The dissolution time can be modified for a rapid effect or for sustained release. Special coatings can make the tablet resistant to the stomach acids such that it only disintegrates in the duodenum, jejunum and colon as a result of enzyme action or alkaline pH. Pills can be coated with sugar, varnish, or wax to disguise the taste ...

  8. Aspirin can help reduce risk of second heart attack, but ...

    www.aol.com/aspirin-help-reduce-risk-second...

    The US Preventive Services Task Force recommends against adults 60 and older starting on low-dose aspirin for the primary prevention of cardiovascular disease, and for people ages 40 to 59 who ...

  9. Bioavailability - Wikipedia

    en.wikipedia.org/wiki/Bioavailability

    The drug formulation (immediate release, excipients used, manufacturing methods, modified release – delayed release, extended release, sustained release, etc.) Whether the formulation is administered in a fed or fasted state; Gastric emptying rate; Circadian differences; Interactions with other drugs/foods:

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