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Thyroid diseases are highly prevalent worldwide, [10] [11] [12] and treatment varies based on the disorder. Levothyroxine is the mainstay of treatment for people with hypothyroidism, [13] while people with hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid ...
Congenital iodine deficiency syndrome (CIDS), also called cretinism, [2] is a medical condition present at birth marked by impaired physical and mental development, due to insufficient thyroid hormone production (hypothyroidism) often caused by insufficient dietary iodine during pregnancy.
Because the treatment is simple, effective, and inexpensive, most of the developed world utilizes newborn screening with blood thyroid stimulating hormone (TSH) levels to detect congenital hypothyroidism. Most children with congenital hypothyroidism correctly treated with thyroxine grow and develop normally in all respects.
Of people with subclinical hypothyroidism, 80% have a TSH level below the 10 mIU/L mark regarded as the threshold for treatment. [50] Children with subclinical hypothyroidism often return to normal thyroid function, and a small proportion develops overt hypothyroidism (as predicted by evolving antibody and TSH levels, the presence of celiac ...
Both NTIS and primary hypothyroidism may have reduced fT3 and fT4, and elevated TSH (which is common in the hospital, during the recovery phase of NTIS). [2] Prescribing thyroxine to treat this may lead to lifelong thyroid overtreatment. [2] Hyperthyroidism may be assumed due to decreased TSH and a transient fT4 increase.
Many children diagnosed with Hashimoto's disease will experience the same progressive course of the disease that adults do. [114] However, of children who develop anti-thyroid antibodies and hypothyroidism, up to 50% are later observed to have normal antibodies and thyroid hormone levels. [5]
Another treatment of AIT involves surgically removing the fistula. This treatment is often the option recommended for children. [2] However, in cases of an antibiotic resistant infection or necrotic tissue, a lobectomy is recommended. [4] If diagnosis and/or treatment is delayed, the disease could prove fatal. [5]
The severity of these symptoms are determined by the period of hypothyroidism and the degree of deficiency of thyroid hormones. [10] It may also include macroglossia. [11] EMG is either normal or may show myopathic low amplitude and short duration motor unit action potentials (MUAPS). [12] The enzymes creatine kinase is elevated usually.