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General structure of an amide (specifically, a carboxamide) Formamide, the simplest amide Asparagine (zwitterionic form), an amino acid with a side chain (highlighted) containing an amide group. In organic chemistry, an amide, [1] [2] [3] also known as an organic amide or a carboxamide, is a compound with the general formula R−C(=O)−NR′R ...
Structures of three kinds of amides: an organic amide (carboxamide), a sulfonamide, and a phosphoramide. In chemistry, the term amide (/ ˈ æ m aɪ d / or / ˈ æ m ɪ d / or / ˈ eɪ m aɪ d /) [1] [2] [3] is a compound with the functional group R n E(=O) x NR 2, where x is not zero, E is some element, and each R represents an organic group or hydrogen. [4]
Amides are the members of a group of organic chemical compounds containing nitrogen. Specifically, an amide results from an acid , in which a carbon atom is double bonded to oxygen and also to a hydroxyl group, when the hydroxyl group is replaced by an amine .
A general linear imide functional group. In organic chemistry, an imide is a functional group consisting of two acyl groups bound to nitrogen. [1] The compounds are structurally related to acid anhydrides, although imides are more resistant to hydrolysis.
The amide bond is synthesized when the carboxyl group of one amino acid molecule reacts with the amino group of the other amino acid molecule, causing the release of a molecule of water (H 2 O), hence the process is a dehydration synthesis reaction. The dehydration condensation of two amino acids to form a peptide bond (red) with expulsion of ...
The −OH group is replaced by an −NH 2 group and the =O group is replaced by =N R, giving amidines the general structure R n E(=NR)NR 2. [ 10 ] [ 11 ] [ 12 ] When the parent oxoacid is a carboxylic acid , the resulting amidine is a carboxamidine or carboximidamide ( IUPAC name).
This amide has two amino groups (– NH 2) joined by a carbonyl functional group (–C(=O)–). It is thus the simplest amide of carbamic acid. [6] Urea serves an important role in the cellular metabolism of nitrogen-containing compounds by animals and is the main nitrogen-containing substance in the urine of mammals.
The structure of nicotinamide consists of a pyridine ring to which a primary amide group is attached in the meta position. It is an amide of nicotinic acid. [7] As an aromatic compound, it undergoes electrophilic substitution reactions and transformations of its two functional groups.