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Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. Ambroxol is often administered as an active ingredient in cough syrup. It was patented in 1966 and came into medical use in 1979. [1]
ATC code R05 Cough and cold preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Examples are carbocisteine, ambroxol, and bromhexine. Expectorants are substances claimed to make coughing easier while enhancing the production of mucus and phlegm. Two examples are acetylcysteine and guaifenesin. Antitussives, or cough suppressants, are substances which suppress the coughing itself.
Ambroxide, widely known by the brand name Ambroxan, is a naturally occurring terpenoid and one of the key constituents responsible for the odor of ambergris.It is an autoxidation product of ambrein. [2]
Mucoactive agents—expectorants—include mucolytics, secretolytics and mucokinetics (also called secretomotorics) [3]. Mucolytics: thin (reduce the viscosity of) mucus [2]
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Bromhexine is intended to support the body's mechanisms for clearing mucus from the respiratory tract.It is secretolytic, increasing the production of serous mucus in the respiratory tract, which makes the phlegm thinner and less viscous.