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Then in 1883, Max Bockhart proved conclusively that the bacterium isolated by Albert Neisser was the causative agent of the disease known as gonorrhea by inoculating the penis of a healthy man with the bacteria. [9] The man developed the classic symptoms of gonorrhea days after, satisfying the last of Koch's postulates. Until this point ...
Genetic transformation is the process by which a recipient bacterial cell takes up DNA from a neighboring cell and integrates this DNA into the recipient’s genome by recombination. In N. meningitidis and N. gonorrhoeae, DNA transformation requires the presence of short DNA sequences (9-10 monomers residing in coding regions) of the donor DNA.
Gonorrhoea or gonorrhea, colloquially known as the clap, [7] is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae. [8] Infection may involve the genitals, mouth, or rectum. [9] Gonorrhea is spread through sexual contact with an infected person, [1] or from a mother to a child during birth. [1]
Micrograph of a clue cell (center), covered in bacteria, as compared to an unremarkable squamous cell at bottom left, and a neutrophil at bottom center. Pap stain Phase contrast microscopy of clue cells in a vaginal swab. Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria ...
Symptoms of gonorrhea usually appear two to five days after contact with an infected partner; however, some men might not notice symptoms for up to a month. Symptoms in men include burning and pain while urinating, increased urinary frequency, discharge from the penis (white, green, or yellow in color), red or swollen urethra, swollen or tender ...
Sarcina cells, for example, are arranged in cubical pockets because cell division alternates regularly among the three perpendicular planes. Streptococcus spp. resemble a string of beads because division always occurs in the same plane. Some of these strings, for example, S. pneumoniae, are only two cells long.
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MALDI-TOF (Matrix-assisted laser desorption/ionization - time of flight) is a specific type of mass spectrometry that is able to identify microorganisms. A pure culture is isolated and spread directly on a stainless steel or disposable target. The cells are lysed and overlaid with a matrix, which forms protein complexes with the bacterial proteins.