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Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. [ 25 ]
Insomnia is one of the most common sleep disorders, with the Centers for Disease Control and Prevention reporting that as many as one in two adults experience short-term bouts, while one in 10 may ...
Over time, insomnia can also contribute to chronic health issues like heart disease, high blood pressure, obesity, chronic pain syndrome and diabetes. What are the causes or risk factors for insomnia?
Aponal, Quitaxon, Sinequan – a tricyclic antidepressant used to treat nerve pain, insomnia; similar to imipramine; Anquil – an antipsychotic primarily used to control antisocial hypersexual behaviour; Aricept – used to slow the progression of Alzheimer's disease
A new study reveals a shocking potential cause for insomnia.
Psychophysiological insomnia is anxiety-induced. Idiopathic insomnia generally begins in childhood and lasts for the rest of a person's life. It's suggested that idiopathic insomnia is a neurochemical problem in a part of the brain that controls the sleep-wake cycle, resulting in either under-active sleep signals or over-active wake signals.
In a mouse study, researchers found that zolpidem (Ambien), a common sleep aid, could prevent the brain from effectively clearing up 'waste', though it remains unclear whether this could affect ...
SNRIs are delivered orally, usually in the form of capsules or tablets. It is recommended to take SNRIs in the morning with breakfast, which does not affect drug levels, but may help with certain side effects. [48] Norepinephrine has activating effects in the body and therefore can cause insomnia in some patients if taken at bedtime. [49]