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In a separate study of men from the pre prostate cancer screening era managed with watchful waiting (56% over age 70 years), progression to distant metastasis or prostate cancer death was 13.9% and 12.3%, respectively for Gleason score 6 or below, but considerably higher at 18.2 and 22.7%, 30% and 20%, 44.4% and 55.6% for Gleason 3+4, 4+3, and ...
LDR prostate brachytherapy (seed or polymer source implantation) is a very effective treatment for low to high risk localized cancer, with patients rapidly returning to normal activities. [15] Although patients may experience urinary problems for the first six months or so after their implant, these usually settle down and lasting problems are ...
The system is widely accepted and used for clinical decision making even as it is recognised that certain biomarkers, like ACP1 expression, might yield higher predictive value for future disease course. [2] The histopathologic diagnosis of prostate cancer has implications for the possibility and methodology of Gleason scoring. [3]
Ly6 proteins are characterized by the LU domain.Typically, they contain one LU domain, but some members of the family have multiple LU domains.The LU domain consists of 60-80 AA and contains 10 cysteines arranged in a specific pattern that allows the creation of 5 disulfide bridges which in turn allow the formation of a three-fingered (3F) structural motif.
The simple blood draw detects a protein produced by cells in the prostate gland, with a rise often signaling prostate cancer. After the approval, prostate cancer diagnosis rates began to rise swiftly.
A subsequent increase in PSA levels by 2.0 ng/mL [disputed – discuss] above the nadir is the currently accepted definition of prostate cancer recurrence after radiation therapy. [citation needed] Recurrent prostate cancer detected by a rise in PSA levels after curative treatment is referred to as a "biochemical recurrence". The likelihood of ...
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