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This is the timeline of modern [clarification needed] antimicrobial [clarification needed] (anti-infective) therapy. The years show when a given drug was released onto the pharmaceutical market. This is not a timeline of the development of the antibiotics themselves.
The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. Following the production of a relatively pure compound in 1942, penicillin was the first naturally-derived antibiotic.
In 1907 Alfred Bertheim synthesized Arsphenamine, the first man-made antibiotic. In 1927 Erik Rotheim patented the first aerosol spray can. In 1933 Robert Pauli Scherer created a method to develop softgels. William Roberts studies about penicillin were continued by Alexander Fleming, who in 1928 concluded that penicillin had an antibiotic ...
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On March 14, 1942, the first patient was treated for streptococcal sepsis with US-made penicillin produced by Merck & Co. [98] Half of the total supply produced at the time was used on that one patient, Anne Miller. [99] By June 1942, just enough US penicillin was available to treat ten patients. [100]
“Antibiotics are chosen very carefully based on the patient being treated — e.g., age, weight, kidney function — the type of infection being treated and the bacteria causing the infection ...
Common forms of antibiotic misuse include excessive use of prophylactic antibiotics in travelers and failure of medical professionals to prescribe the correct dosage of antibiotics on the basis of the patient's weight and history of prior use. Other forms of misuse include failure to take the entire prescribed course of the antibiotic ...
Timeline of UnitedHealthcare CEO shooting. Map shows all the whereabouts of the suspect in the shooting death of UnitedHealthcare CEO Brian Thompson. / Credit: CBS News Confirmed.