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Pre-eclampsia is a multi-system disorder specific to pregnancy, characterized by the new onset of high blood pressure and often a significant amount of protein in the urine or by the new onset of high blood pressure along with significant end-organ damage, with or without the proteinuria.
Generally, in mothers with preeclampsia, labor is induced once the gestational age is >37 weeks. [13] In patients with preeclampsia with severe features or eclampsia, labor is induced once the gestational age is >34 weeks. [13] In patients with gestational hypertension and no other signs of severe disease, labor is generally induced at term. [13]
HELLP syndrome occurs in about 0.7% of pregnancies and affects about 15% of women with eclampsia or severe pre-eclampsia. [5] [2] Death of the mother is uncommon (< 1%). [1] [3] Outcomes in the babies are generally related to how premature they are at birth. [1] The syndrome was first named in 1982 by American gynaecologist Louis Weinstein. [2]
The causes of preeclampsia and HELLP syndrome are unknown, but those dealing with diabetes, obesity, high blood pressure and having multiples (twins, triplets etc.) are at greater risk.
While seizures are most common in the third trimester, they may occur any time from 20 weeks of pregnancy until 6 weeks after birth. [50] Because pre-eclampsia and eclampsia are common conditions in women, eclampsia can be assumed to be the correct diagnosis until proven otherwise in pregnant or postpartum women who experience seizures. [51]
Preeclampsia is one of the leading causes of pregnancy complications. The newly approved blood test that detects it might help The post A new blood test can help diagnose preeclampsia in pregnant ...
The mechanism of preeclampsia/eclampsia is unknown, but consequences if left untreated can include fetal growth restriction or death, as well as pose medical risks to the mother. Signs and symptoms of preeclampsia can include swelling, protein in the urine, headaches, vomiting, and abnormal labs that assess kidney and liver function, some of ...
Treatment of this condition is very similar to treatment of non-gravid heart failure patients, however, safety of the fetus must be prioritized. For example, for anticoagulation due to increased risk for thromboembolism, low molecular weight heparin which is safe for use during pregnancy is used instead of warfarin which crosses the placenta.