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Neuroleptic malignant syndrome (NMS) is a rare [5] [6] but life-threatening reaction that can occur in response to antipsychotics (neuroleptic) or other drugs that block the effects of dopamine. [ 1 ] [ 7 ] Symptoms include high fever , confusion, rigid muscles, variable blood pressure, sweating, and fast heart rate. [ 1 ]
This is a general list of long-term side effects associated with Antipsychotic (neuroleptic) medication. Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage.
Sepsis, encephalitis, neuroleptic malignant syndrome, [8] malignant hyperthermia, [8] lethal catatonia, spinal cord injury (not associated with PSH), seizures, and hydrocephalus (this can be associated with PSH) are examples of diagnoses that should be considered due to the manifestation of similar symptoms before confirming a diagnosis of PSH. [3]
The recovery process from anti-NMDAR encephalitis can take many months depending on its form and severity. The symptoms may reappear in reverse order: The patient may begin to experience psychosis again, leading many people to falsely believe the patient is not recovering. As the recovery process continues on, the psychosis fades.
A rare but potentially lethal condition of neuroleptic malignant syndrome (NMS) has been associated with the use of antipsychotics. Through its early recognition, and timely intervention rates have declined. However, an awareness of the syndrome is advised to enable intervention. [112]
Serious side effects may include the potentially permanent movement disorder tardive dyskinesia, neuroleptic malignant syndrome, severe lowering of the seizure threshold, and low white blood cell levels. [6] In older people with psychosis as a result of dementia, it may increase the risk of death. [6] It is unclear if it is safe for use in ...
People with Lewy body dementias who take neuroleptics are at risk for neuroleptic malignant syndrome, a life-threatening illness. [51] There is no evidence to support the use of antipsychotics to treat the Lewy body dementias, [10] and they carry the additional risk of stroke when used in the elderly with dementia. [86]
These mothers require sedation with anti-psychotic (neuroleptic) agents, but are liable to extrapyramidal symptoms, [51]: 228 including neuroleptic malignant syndrome. [90] Since the link with bipolar disorder was recognized (about 1970), treatment with mood-stabilizing agents, such as lithium [ 72 ] : 20–23 and anti-convulsant drugs, has ...