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  2. Ribosome - Wikipedia

    en.wikipedia.org/wiki/Ribosome

    Free and membrane-bound ribosomes differ only in their spatial distribution; they are identical in structure. Whether the ribosome exists in a free or membrane-bound state depends on the presence of an ER-targeting signal sequence on the protein being synthesized, so an individual ribosome might be membrane-bound when it is making one protein ...

  3. P-site - Wikipedia

    en.wikipedia.org/wiki/P-site

    The complete three-dimensional structure of the T. thermophilus 70S ribosome was determined using X-ray crystallography, containing mRNA and tRNAs bound to the P and E sites at 5.5 Å resolution and to the A site at 7 Å resolution. Authors found that all three tRNA binding sites (A, P, and E) of the ribosome contact all three respective tRNAs ...

  4. Membrane bound polyribosome - Wikipedia

    en.wikipedia.org/wiki/Membrane_bound_polyribosome

    The polypeptides ribosomes produce go on to be cell structural proteins, enzymes, and many other things. [3] Ribosomes can also sometimes be associated with chloroplasts and mitochondria but these are not membrane bound. [3] The image shows a membrane-bound ribosome synthesizing a protein into the lumen of the endoplasmic reticulum.

  5. Eukaryotic ribosome - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_ribosome

    The complete structure of the eukaryotic 80S ribosome from the yeast Saccharomyces cerevisiae was obtained by crystallography at 3.0 A resolution. [18] These structures reveal the precise architecture of eukaryote-specific elements, their interaction with the universally conserved core, and all eukaryote-specific bridges between the two ...

  6. 18S ribosomal RNA - Wikipedia

    en.wikipedia.org/wiki/18S_ribosomal_RNA

    The integral role in formation and function of the ribosome is a key cause for its omnipresence in eukaryotic life. Meanwhile, the gene maintains a high degree of conservation under a persistent selective pressure in all living beings, [ 1 ] highlighting its potential for comparison between distantly related clades.

  7. Eukaryotic small ribosomal subunit (40S) - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_Small_Ribosomal...

    The eukaryotic small ribosomal subunit (40S) is the smaller subunit of the eukaryotic 80S ribosomes, with the other major component being the large ribosomal subunit (60S). The "40S" and "60S" names originate from the convention that ribosomal particles are denoted according to their sedimentation coefficients in Svedberg units.

  8. Macromolecular assembly - Wikipedia

    en.wikipedia.org/wiki/Macromolecular_assembly

    In molecular biology, the term macromolecular assembly (MA) refers to massive chemical structures such as viruses and non-biologic nanoparticles, cellular organelles and membranes and ribosomes, etc. that are complex mixtures of polypeptide, polynucleotide, polysaccharide or other polymeric macromolecules.

  9. Polysome - Wikipedia

    en.wikipedia.org/wiki/Polysome

    Several ribosomes synthesizing a polypeptide on the same mRNA strand. A polyribosome (or polysome or ergosome) is a group of ribosomes bound to an mRNA molecule like “beads” on a “thread”. [1] It consists of a complex of an mRNA molecule and two or more ribosomes that act to translate mRNA instructions into polypeptides.

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