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Acute GPP typically requires inpatient management including both topical and systemic therapy, and supportive measures. [3] Systemic glucocorticoid withdrawal is a common causative agent. [ 4 ] Withdrawal or administration of certain drugs in the patient's previous medication regimen may be required.
Generalized pustular psoriasis (GPP) is a rare type of psoriasis that can present in a variety of forms. [1] Unlike the most general and common forms of psoriasis, GPP usually covers the entire body and with pus-filled blisters rather than plaques. GPP can present at any age, but is rarer in young children.
The diagnosis of AGEP may be forthright in typical cases in which an individual: has taken a drug known to cause the disorder; develops multiple sterile pustules overlying large areas of red swollen skin starting a few days after initial drug intake; and has a histology of biopsied lesions that shows pustules just below the skin's Stratum ...
Pustulosis is highly inflammatory skin condition resulting in large fluid-filled blister-like areas - pustules. Pustulosis typically occurs on the palms of the hands and/or the soles of the feet. The skin of these areas peels and flakes . [1]
Pustule: A pustule is a small elevation of the skin usually consisting of necrotic inflammatory cells. [30] Cyst: A cyst is an epithelial-lined cavity. [10] Wheal: A wheal is a rounded or flat-topped, pale red papule or plaque that is characteristically evanescent, disappearing within 24 to 48 hours.
Occasionally, perifollicular abscesses may be present when pustules and papules are the dominant clinical findings. [ 7 ] There is a possible discovery of new information that the perioral dermatitis develops due to damage to the skin barrier in the facial area, which possibly led to the patients become expose to both the internal and external ...
Fibrous papule of the nose is a harmless small bump on or near the nose. It is typically dome-shaped, skin-colored, white or reddish, smooth and firm. [1] [2] Less frequently it can occur elsewhere on the face. [3] Sometimes there are a few. [1] It may be shiny and remains unchanged for life. There may be a central hair. [3]
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...