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praziquantel – treatment of infestations of the tapeworms Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus; prazosin – sympatholytic used in hypertension and abnormal muscle contractions; prednisolone – glucocorticoid (steroid) used in the management of inflammation and auto-immune disease, primarily in cats
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 acetate ester of methylprednisolone—which is used in clinical and veterinary medicine.
Feline idiopathic cystitis begins as an acute non-obstructive episode and is self-limiting in about 85% of cases, resolving itself in a week. In approximately 15% of cases, it can escalate into an obstructive episode ("blocked cat") which can be life-threatening for a male cat. [5]
Prednisolone has a relatively short half-life, ranging 2–4 hours. It also has a large therapeutic window, considering the dosage required to produce a therapeutic effect is a few times higher than what the body naturally produces. [14] Prednisolone is 70–90% plasma protein bound, it binds to proteins such as albumin. [14]
Although cats are obligate carnivores, vegetarian and vegan cat food are preferred by owners uncomfortable with feeding animal products to their pets. The U.S. Food and Drug Administration Center for Veterinary Medicine has come out against vegetarian cat and dog food for health reasons. Cats require high levels of taurine in their diet.
Prednisone is a prodrug and must be converted to prednisolone by the liver before it becomes active. [6] [7] Prednisolone then binds to glucocorticoid receptors, activating them and triggering changes in gene expression. [4] Prednisone was patented in 1954 and approved for medical use in the United States in 1955.
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
Cats with chronic feline lower urinary tract disease caused by struvite uroliths are sometimes treated with a lifelong diet of prescription wet food as these special diets acidify urine which dissolve struvite. However ordinary wet food with high moisture content and rich in animal protein can be just as effective in many cases as it keeps the ...