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However the thickness of the RNFL also decreases with age and not visual acuity. [3] The sparing of this layer is important in the treatment of the disease as it is the basis for connecting retinal prostheses to the optic nerve, or implanting stem cells that could regenerate the lost photoreceptors.
The symptoms of low back pain usually improve within a few weeks from the time they start, with 40–90% of people recovered by six weeks. [2] In most episodes of low back pain a specific underlying cause is not identified or even looked for, with the pain believed to be due to mechanical problems such as muscle or joint strain.
Weight loss, to relieve symptoms and slow the progression of the stenosis; Physical therapy to support self-care. [37] Also may give instructions on stretching and strength exercises that may lead to a decrease in pain and other symptoms. Lumbar epidural steroid or anesthetic injections have low quality evidence to support their use. [36] [38]
Pain is a common symptom in MS. A 2013 study which systematically pooled results from 28 studies (7101 patients) estimated that pain affected 63% of people with MS. [97] These 28 studies described pain in a large range of different people with MS. The authors found no evidence that pain was more common in people with progressive types of MS, in ...
Moderate-to-severe cases can cause radicular pain in the legs caused by nerve root compression. [5] The symptoms are usually exacerbated by upright posture and often, but not always, relieved by lying down. Postural headaches can be related to spontaneous spinal cerebrospinal fluid leaks. [6] However, in many patients, dural ectasia is ...
Spinal stenosis began to be recognized as an impairing condition in the 1950s and 1970s. Individuals who experience back pain and other symptoms are likely to have bigger spinal canals than those who are asymptomatic. [45] A normal-sized lumbar canal is rarely encountered in persons with either disc disease or those requiring a laminectomy. [31]
The thoracic spine begins at the base of the neck and extends to the middle of the trunk. Any pain in this area is considered "middle back pain". [2] The exact symptoms associated with middle back pain will depend upon the underlying cause. Most middle back pain is not serious in nature.
After age 50 or 60, osteoarthritic degeneration (spondylosis) or spinal stenosis are more likely causes of low back pain or leg pain. 4.8% of males and 2.5% of females older than 35 experience sciatica during their lifetime. Of all individuals, 60% to 80% experience back pain during their lifetime. In 14%, pain lasts more than two weeks.
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