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  2. Hemagglutination assay - Wikipedia

    en.wikipedia.org/wiki/Hemagglutination_assay

    HA and HAI apply the process of hemagglutination, in which sialic acid receptors on the surface of red blood cells (RBCs) bind to the hemagglutinin glycoprotein found on the surface of influenza virus (and several other viruses) and create a network, or lattice structure, of interconnected RBCs and virus particles. [2]

  3. Hemagglutination - Wikipedia

    en.wikipedia.org/wiki/Hemagglutination

    In blood grouping, the patient's serum is tested against RBCs of known blood groups and also the patient's RBCs are tested against known serum types. In this way the patient's blood group is confirmed from both RBCs and serum. A direct Coombs test is also done on the patient's blood sample in case there are any confounding antibodies.

  4. Hemagglutinin - Wikipedia

    en.wikipedia.org/wiki/Hemagglutinin

    This results in new subtype of hemagglutinins being created frequently, and is the cause of seasonal influenza outbreaks in humans. [14] Measles hemagglutinin: a hemagglutinin produced by the measles virus [15] that encodes six structural proteins, with hemagglutinin and fusion proteins being surface glycoproteins involved in attachment and ...

  5. Hemagglutinin (influenza) - Wikipedia

    en.wikipedia.org/wiki/Hemagglutinin_(influenza)

    Influenza hemagglutinin (HA) or haemagglutinin [p] (British English) is a homotrimeric glycoprotein found on the surface of influenza viruses and is integral to its infectivity. Hemagglutinin is a class I fusion protein , [ 1 ] [ 2 ] having multifunctional activity as both an attachment factor and membrane fusion protein .

  6. Agglutination (biology) - Wikipedia

    en.wikipedia.org/wiki/Agglutination_(biology)

    The result is blood group A positive. Hemagglutination is the process by which red blood cells agglutinate, meaning clump or clog. The agglutin involved in hemagglutination is called hemagglutinin. In cross-matching, donor red blood cells and the recipient's serum or plasma are

  7. Coombs test - Wikipedia

    en.wikipedia.org/wiki/Coombs_test

    The direct Coombs test is used to detect antibodies or complement proteins attached to the surface of red blood cells. To perform the test, a blood sample is taken and the red blood cells are washed (removing the patient's plasma and unbound antibodies from the red blood cells) and then incubated with anti-human globulin ("Coombs reagent").

  8. Phytohaemagglutinin - Wikipedia

    en.wikipedia.org/wiki/Phytohaemagglutinin

    In medicine these proteins are useful and are used as a mitogen to trigger T-lymphocyte cell division and to activate latent HIV-1 from human peripheral lymphocytes.In neuroscience, anterograde tracing is a research method that uses the protein product phytohaemagglutinin PHA-L as a molecular tracer that can be taken up by the cell and transported across the synapse into the next cell thereby ...

  9. Epitope mapping - Wikipedia

    en.wikipedia.org/wiki/Epitope_mapping

    In immunology, epitope mapping is the process of experimentally identifying the binding site, or epitope, of an antibody on its target antigen (usually, on a protein). [ 1 ] [ 2 ] [ 3 ] Identification and characterization of antibody binding sites aid in the discovery and development of new therapeutics , vaccines , and diagnostics .