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Charles River was founded in 1947 by Henry Foster, a young veterinarian who purchased one thousand rat cages from a Virginia farm and set up a one-person laboratory in Boston overlooking the Charles River. To fulfill the regional need for laboratory animal models, he bred, fed, and cared for the animals and personally delivered them to local ...
FVB mice show above average activity and anxiety. [3] Because of their visual impairment, they do not show normal circadian rhythms. [4] For the same reason, they struggle with visual tasks such as the Morris watermaze.
The C57BL/6 mouse was the second-ever mammalian species to have its entire genome published. [ 1 ] The dark coat makes the mouse strain convenient for creating transgenic mice: it is crossed with a light-furred 129 mouse, and the desirable crosses can be easily identified by their mixed coat colors.
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BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation.
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James Clifford Foster is the chairman and chief executive officer of Charles River Laboratories, Inc., an international company that works on the drug discovery and development process. Charles River Laboratories is the world's largest breeder of animals for use in laboratory experimentation.