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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
The protein has several domains of which domain D1 contains the polio virus binding site. Within this domain, 37 amino acids are responsible for binding the virus. Poliovirus is an enterovirus. Infection occurs via the fecal–oral route, meaning that one ingests the virus and viral replication occurs in the gastrointestinal tract. [42]
Polio is an infection caused by a virus that mostly affects children under 5. Most people infected with polio don’t have any symptoms, but it can cause fever, headaches, vomiting and stiffness ...
In 1949, John F. Enders (1897–1985) Thomas Weller (1915–2008), and Frederick Robbins (1916–2003) grew polio virus for the first time in cultured human embryo cells, the first virus to be grown without using solid animal tissue or eggs. Infections by poliovirus most often cause the mildest of symptoms.
An unvaccinated NY man has polio, the first documented case in the U.S. since 2013. Here, doctors explain what polio is, its causes, symptoms, and vaccines.
Poliomyelitis, or polio, is a distinctly contagious illness caused by a virus called poliovirus. The virus targets the nervous system, which is why it sometimes triggers spinal and respiratory ...
The common factors in the fecal-oral route can be summarized as five Fs: fingers, flies, fields, fluids, and food. Diseases caused by fecal-oral transmission include typhoid, cholera, polio, hepatitis and many other infections, especially ones that cause diarrhea.
Non-polio enteroviruses, like EV-D68, cause about 10 to 15 million infections and tens of thousands of hospitalizations each year across the US. EV-D68 was first identified in California in the ...