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Contextualism, also known as epistemic contextualism, is a family of views in philosophy which emphasize the context in which an action, utterance, or expression occurs. Proponents of contextualism argue that, in some important respect, the action, utterance, or expression can only be understood relative to that context. [ 1 ]
Functional contextualism is a modern philosophy of science [1] rooted in philosophical pragmatism and contextualism. It is most actively developed in behavioral science in general and the field of behavior analysis and contextual behavioral science in particular (see the entry for the Association for Contextual Behavioral Science ).
In eukaryotic cells the primary transcript is pre-mRNA. Pre-mRNA must be processed for translation to proceed. Processing includes the addition of a 5' cap and a poly-A tail to the pre-mRNA chain, followed by splicing. Alternative splicing occurs when appropriate, increasing the diversity of the proteins that any single mRNA can produce. The ...
During chain elongation, each additional amino acid is added to the nascent polypeptide chain in a three-step microcycle. The steps in this microcycle are (1) positioning the correct aminoacyl-tRNA in the A site of the ribosome, which is brought into that site by eEF1, (2) forming the peptide bond, and (3) shifting the mRNA by one codon ...
World Hypotheses: A Study in Evidence, by Stephen C. Pepper (1942), presents four relatively adequate world hypotheses (or world views or conceptual systems) in terms of their root metaphors: formism (similarity), mechanism (machine), contextualism (historical act), and organicism (living system).
Autocrine signaling occurs when the chemical signal acts on the same cell that produced the signaling chemical. [1] Intracrine signaling occurs when the chemical signal produced by a cell acts on receptors located in the cytoplasm or nucleus of the same cell. [2] Juxtacrine signaling occurs between physically adjacent cells. [3]
Direct contact between cells allows the receptors on one cell to bind the small molecules attached to the plasma membrane of different cell. In eukaryotes, many of the cells during early development communicate through direct contact. [5] Synaptic signaling, an integral part of nervous system activity, occurs between neurons and target
The 3'-5' action of DNA polymerase along the parent strand leaves a short single-stranded DNA (ssDNA) region at the 3' end of the parent strand when the Okazaki fragments have been repaired. Since replication occurs in opposite directions at opposite ends of parent chromosomes, each strand is a lagging strand at one end.