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A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Organizations and companies operating in cannabis markets have pushed education and marketing of terpenes in their products as a way to differentiate taste and effects of cannabis. [24] The entourage effect , which describes the synergy of cannabinoids, terpenes, and other plant compounds, has also helped further awareness and demand for ...
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
The earliest systematic studies of physiological effects of cannabis-derived chemical were conducted in the 1920's (see Fig. The number of publications about marijuana/cannabis). The level or research activity in this area remained relatively low and constant until 1966, when a 10-fold increase in publication activity occurred within 10 years.
Typically, adverse effects of medical cannabis use are not serious; [6] they include tiredness, dizziness, increased appetite, and cardiovascular and psychoactive effects. Other effects can include impaired short-term memory; impaired motor coordination; altered judgment; and paranoia or psychosis at high doses. [ 44 ]
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THC is a lipophilic molecule [27] and may bind non-specifically to a variety of entities in the brain and body, such as adipose tissue (fat). [ 28 ] [ 29 ] THC, as well as other cannabinoids that contain a phenol group, possess mild antioxidant activity sufficient to protect neurons against oxidative stress , such as that produced by glutamate ...
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