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Parinaud syndrome is a relatively uncommon neuroophthalmologic syndrome named for French ophthalmologist, Henri Parinaud. Parinaud syndrome has been known by many different names including dorsal midbrain syndrome, Sylvian aqueduct syndrome, pretectal syndrome, and Koerber-Salus-Elschnig syndrome.
Background: Dorsal midbrain syndrome (DMS) consists of a constellation of clinical features, including reduced upgaze, pupillary light-near dissociation, lid retraction, convergence retraction, and eye misalignment.
Dorsal midbrain syndrome (DMS) consists of a constellation of clinical features, including reduced upgaze, pupillary light-near dissociation, lid retraction, convergence retraction, and eye misalignment.
Parinaud syndrome is also known as sylvian aqueduct syndrome, dorsal midbrain syndrome, pretectal syndrome, and Koerber-Salus-Elschnig syndrome. Parinaud syndrome is classically described by the triad of impaired upward gaze, convergence retraction nystagmus, and pupillary hyporeflexia.
Parinaud syndrome (also called Parinaud’s syndrome and dorsal midbrain syndrome) is a rare neurological disorder that causes upward gaze palsy (the inability to gaze upward). It can also include convergence-retraction nystagmus, bilateral eyelid retraction and light-near dissociation of the pupils. The condition was named for a French ...
Parinaud's syndrome is a constellation of neurological signs indicating injury to the dorsal midbrain. More specifically, compression of the vertical gaze center at the rostral interstitial nucleus of medial longitudinal fasciculus (riMLF).
In Parinaud’s syndrome or dorsal midbrain syndrome, the two structures that are mainly and causally involved in the symptomatology are the midbrain and the pineal gland. The midbrain can be divided into two segments: the tegmentum or ventral portion and the tectum or dorsal portion.
Dorsal midbrain syndrome, also known as Parinaud syndrome—after Henri Parinaud (1844–1905), the French ophthalmologist—may have the following features: (1) vertical gaze palsy, (2) convergence-retraction nystagmus, (3) pupil light–near dissociation and (4) eyelid retraction (Collier’s sign).1
Parinaud syndrome, also known as dorsal midbrain syndrome, is a supranuclear vertical gaze disturbance caused by pathology of the dorsal midbrain region, often, but not exclusively, via compression of the superior tectal plate.
Dorsal midbrain syndrome (aka Parinaud’s syndrome) is classically the triad of up gaze palsy, convergence retraction nystagmus, and light-near dissociation. While there are many different etiologies, the most common causes are pineal region tumor, midbrain hemorrhage, midbrain infarct, and midbrain tumor.