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  2. Uric acid - Wikipedia

    en.wikipedia.org/wiki/Uric_acid

    Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C 5 H 4 N 4 O 3. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. [1]

  3. Hyperuricemia - Wikipedia

    en.wikipedia.org/wiki/Hyperuricemia

    Hyperuricaemia or hyperuricemia is an abnormally high level of uric acid in the blood. In the pH conditions of body fluid, uric acid exists largely as urate, the ion form. [1][2] Serum uric acid concentrations greater than 6 mg/dL for females, 7 mg/dL for males, and 5.5 mg/dL for youth (under 18 years old) are defined as hyperuricemia. [3]

  4. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    1–2% (developed world) [ 7 ] Gout (/ ɡaʊt / GOWT[ 9 ]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [ 4 ][ 10 ] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [ 11 ]

  5. Xanthine oxidase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Xanthine_oxidase_inhibitor

    A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism.In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. [1]

  6. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...

  7. Uricosuric - Wikipedia

    en.wikipedia.org/wiki/Uricosuric

    Uricosuric medications (drugs) are substances that increase the excretion of uric acid in the urine, thus reducing the concentration of uric acid in blood plasma. In general, this effect is achieved by action on the proximal tubule of the kidney. Drugs that reduce blood uric acid are not all uricosurics; blood uric acid can be reduced by other ...

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