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  2. Carvedilol - Wikipedia

    en.wikipedia.org/wiki/Carvedilol

    Carvedilol is a nonselective beta blocker and alpha-1 blocker. [5] How it improves outcomes is not entirely clear but may involve dilation of blood vessels. [5] Carvedilol was patented in 1978 and approved for medical use in the United States in 1995. [5] [8] It is on the World Health Organization's List of Essential Medicines. [9]

  3. Maintenance dose - Wikipedia

    en.wikipedia.org/wiki/Maintenance_dose

    This is not to be confused with dose regimen, which is a type of drug therapy in which the dose [mg] of a drug is given at a regular dosing interval on a repetitive basis. Continuing the maintenance dose for about 4 to 5 half-lives (t 1/2 ) of the drug will approximate the steady state level. [ 1 ]

  4. Atenolol - Wikipedia

    en.wikipedia.org/wiki/Atenolol

    This in turn may result in fewer effects in the central nervous system as well as a lower risk of neuropsychiatric side effects. [44] Only small amounts of atenolol are said to enter the brain. [ 2 ] [ 3 ] The brain-to-blood ratio of atenolol was 0.2 : 1 in one study, whereas the ratio for propranolol was 33 : 1 in the same study.

  5. Labetalol - Wikipedia

    en.wikipedia.org/wiki/Labetalol

    Labetalol was the first drug created that combined both α- and β-adrenergic receptor blocking properties. It was created to potentially fix the compensatory reflex issue that occurred when blocking a single receptor subtype, i.e. vasoconstriction after blocking β-adrenergic receptors or tachycardia after blocking α-adrenergic receptors.

  6. Clomipramine - Wikipedia

    en.wikipedia.org/wiki/Clomipramine

    Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [7] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [8] body dysmorphic disorder [9] [10] [11] and chronic pain. [7]

  7. Pharmacokinetics of progesterone - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics_of...

    The researchers concluded that the 25 and 50 mg doses would be appropriate for administration three times per day while the 100 mg dose would be appropriate for administration twice per day. [149] The bioavailability of vaginal progesterone gel is about 40-fold greater than that of oral progesterone.

  8. Rick Scott - Wikipedia

    en.wikipedia.org/wiki/Rick_Scott

    This is an accepted version of this page This is the latest accepted revision, reviewed on 7 February 2025. American politician (born 1952) This article is about the American politician and businessman. For other people with similar names, see Richard Scott (disambiguation). Rick Scott Official portrait, 2019 Chair of the Senate Aging Committee Incumbent Assumed office January 3, 2025 Preceded ...

  9. USS Nimitz - Wikipedia

    en.wikipedia.org/wiki/USS_Nimitz

    USS Nimitz (CVN-68) is an aircraft carrier of the United States Navy, and the lead ship of her class.One of the largest warships in the world, she was laid down, launched, and commissioned as CVAN-68, "aircraft carrier, attack, nuclear powered", but she was later redesignated as CVN-68, "aircraft carrier, multi-mission, nuclear-powered", on 30 June 1975, as part of a fleet-wide realignment ...

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