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Mutational studies involving LAT-1 knockout and LAT-2 gene deletion mutants have revealed that the role of latrophilin receptors in the different tissues that they are expressed differs between subtypes, with LAT-1 being expressed in the pharynx of C.elegans (thereby modulating pharyngeal pumping) and LAT-2 having a role in locomotion. [6]
Caenorhabditis elegans (/ ˌ s iː n oʊ r æ b ˈ d aɪ t ə s ˈ ɛ l ə ɡ æ n s / [6]) is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. [7] It is the type species of its genus. [8] The name is a blend of the Greek caeno-(recent), rhabditis (rod-like) [9] and Latin elegans (elegant).
WormBook is an open access, comprehensive collection of original, peer-reviewed chapters covering topics related to the biology of the nematode worm Caenorhabditis elegans (C. elegans). WormBook also includes WormMethods, an up-to-date collection of methods and protocols for C. elegans researchers. [1] [2] [3] [4]
The genus Caenorhabditis contains the noted model organism Caenorhabditis elegans and several other species for which a genome sequence is either available or currently being determined. The two most-studied species in this genus ( C. elegans and C. briggsae ) are both androdioecious (they have male and hermaphrodite sexes) whereas most other ...
Eight pairs of chemosensory neurons in Caenorhabditis elegans take up fluorescein dyes entering through the chemosensory organs. When filled with dye, the processes and cell bodies of these neurons can be examined in live animals by fluorescence microscopy. Using this technique five genes were identified: unc-33, unc-44, unc-51, unc-76, and unc ...
OpenWorm is an international open science project for the purpose of simulating the roundworm Caenorhabditis elegans at the cellular level. [1] [2] [3] Although the long-term goal is to model all 959 cells of the C. elegans, the first stage is to model the worm's locomotion by simulating the 302 neurons and 95 muscle cells.
Much of the functionality of AceDB for C. elegans has been made available through the WormBase database. [3] Features included: a graphical user interface with many specific displays and tools for genomic data; open-source software; package that implements a simple web browser interface allowing the database to accessed from anywhere
Howard Robert Horvitz ForMemRS NAS AAA&S APS NAM (born May 8, 1947) is an American biologist whose research on the nematode worm Caenorhabditis elegans [3] [1] was awarded the 2002 Nobel Prize in Physiology or Medicine, together with Sydney Brenner and John E. Sulston, whose "seminal discoveries concerning the genetic regulation of organ development and programmed cell death" were "important ...