Search results
Results from the WOW.Com Content Network
Conventional drug delivery is limited by the inability to control dosing, target specific sites, and achieve targeted permeability. Traditional methods of delivering therapeutics to the body experience challenges in achieving and maintaining maximum therapeutic effect while avoiding the effects of drug toxicity.
Ultrasound-triggered drug delivery using stimuli-responsive hydrogels refers to the process of using ultrasound energy for inducing drug release from hydrogels that are sensitive to acoustic stimuli. This method of approach is one of many stimuli-responsive drug delivery-based systems that has gained traction in recent years due to its ...
The stimulus–response model is a conceptual framework in psychology that describes how individuals react to external stimuli.According to this model, an external stimulus triggers a reaction in an organism, often without the need for conscious thought.
Drug delivery systems have been around for many years, but there are a few recent applications of drug delivery that warrant 1. Drug delivery to the brain: Many drugs can be harmful when administered systemically; the brain is very sensitive to medications and can easily cause damage if a drug is administered directly into the bloodstream.
This method of drug delivery falls in the category of stimuli-responsive drug delivery systems which include pH, temperature, and redox-responsive systems. Mechanical forces occur naturally throughout the human body therefore, stretch-triggered drug delivery systems may be used to autonomously deliver medications to the body when needed.
Another delivery-release mechanism is activation-modulated drug delivery, where the release is triggered by environmental stimuli. The stimuli can be external, such as the introduction of a chemical activators or activation by light or electromagnetic fields, or biological - such as pH, temperature, and osmotic pressure which can vary widely ...
The conditioned compensatory response model, formed by Siegel (1975), postulates that the conditioned response is opposite to the unconditioned drug effect, such that the conditioned response is part of a homeostatic response resulting in the development of drug tolerance. [8] [12] Each conditioning model is empirically supported. [13]
Stimulus–response (S–R) compatibility is the degree to which a person's perception of the world is compatible with the required action. S–R compatibility has been described as the "naturalness" of the association between a stimulus and its response, such as a left-oriented stimulus requiring a response from the left side of the body.