Search results
Results from the WOW.Com Content Network
[9] Meta-analyses conclude that fluoroquinolones pose little or no additional risk to children compared to other antibiotic classes. [ 10 ] [ 11 ] [ 12 ] Fluoroquinolone use in children may be appropriate when the infection is caused by multidrug-resistant bacteria , or when alternative treatment options require parenteral administration and ...
Oxacillin is a penicillinase-resistant β-lactam.It is similar to methicillin, and has replaced methicillin in clinical use.Other related compounds are nafcillin, cloxacillin, dicloxacillin, and flucloxacillin.
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
The fosfomycin molecule has an epoxide or oxirane ring, which is highly strained and thus very reactive. [citation needed]Fosfomycin has broad antibacterial activity against both Gram-positive and Gram-negative pathogens, with useful activity against E. faecalis, E. coli, and various Gram-negatives such as Citrobacter and Proteus.
The first sulfonamide and the first systemically active antibacterial drug, Prontosil, was developed by a research team led by Gerhard Domagk in 1932 or 1933 at the Bayer Laboratories of the IG Farben conglomerate in Germany, [9] [10] [11] for which Domagk received the 1939 Nobel Prize in Physiology or Medicine. [139]
Children with acute otitis media who are younger than six months of age are generally treated with amoxicillin or other antibiotics. Although most children with acute otitis media who are older than two years old do not benefit from treatment with amoxicillin or other antibiotics, such treatment may be helpful in children younger than two years old with acute otitis media that is bilateral or ...
Sulfonamide functional group Hydrochlorothiazide is a sulfonamide and a thiazide. Furosemide is a sulfonamide, but not a thiazide. Sulfamethoxazole is an antibacterial sulfonamide.
[9] [10] MIC values provide a quantitative measure of an extract or compound's antimicrobial potency. The lower the MIC, the more potent the antimicrobial. [4] When in vitro toxicity data is available, MICs can also be used to calculate selectivity index values, a measure of off-target to target toxicity. [4]