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Whipple's disease is a rare systemic infectious disease caused by the bacterium Tropheryma whipplei.First described by George Hoyt Whipple in 1907 and commonly considered as a gastrointestinal disorder, Whipple's disease primarily causes malabsorption, but may affect any part of the human body, including the heart, brain, joints, skin, lungs and the eyes. [1]
"Tropheryma whipplei" is a bacterium that is the causative organism of Whipple's disease, [1] and rarely, endocarditis. While "T. whipplei" is categorized with the Gram-positive Actinomycetota, the organism is commonly found to be Gram-positive or Gram-indeterminate when stained in the laboratory. [1]
A pancreaticoduodenectomy, also known as a Whipple procedure, is a major surgical operation most often performed to remove cancerous tumours from the head of the pancreas. [2] It is also used for the treatment of pancreatic or duodenal trauma, or chronic pancreatitis . [ 2 ]
George Hoyt Whipple (August 28, 1878 – February 1, 1976) [1] was an American physician, pathologist, biomedical researcher, and medical school educator and administrator.. Whipple shared the Nobel Prize in Physiology or Medicine in 1934 with George Richards Minot and William Parry Murphy "for their discoveries concerning liver therapy in cases of anemi
Whipple's triad is a collection of three signs (called Whipple's criteria) that suggests that a patient's symptoms result from hypoglycaemia that may indicate insulinoma. The essential conditions are symptoms of hypoglycaemia, low blood plasma glucose concentration , and relief of symptoms when plasma glucose concentration is increased.
Some individuals may benefit from diet modification, such as a reduced fat diet, following cholecystectomy. The liver produces bile and the gallbladder acts as reservoir. From the gallbladder, bile enters the intestine in individual portions. In the absence of a gallbladder, bile enters the intestine constantly, but in small quantities.
Allen Oldfather Whipple (September 2, 1881 – April 6, 1963) was an American surgeon who is known for the pancreatic cancer operation which bears his name (the Whipple procedure) as well as Whipple's triad. Whipple was born to missionary parents William Levi Whipple and Mary Louise Whipple (née Allen), in Urmia, West Azerbaijan, Iran.
With a reduced ability to eat a large volume of food, gastric bypass patients must focus on eating their protein requirements first, and with each meal. In some cases, surgeons may recommend the use of a liquid protein supplement. Powdered protein supplements added to smoothies or any food can be an important part of the post-op diet.