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Cortical white matter increases from childhood (~9 years) to adolescence (~14 years), most notably in the frontal and parietal cortices. [8] Cortical grey matter development peaks at ~12 years of age in the frontal and parietal cortices, and 14–16 years in the temporal lobes (with the superior temporal cortex being last to mature), peaking at about roughly the same age in both sexes ...
Brain areas that undergo significant post-natal development, such as those involved in memory and emotion are more vulnerable to effects of early life stress. [ 58 ] [ 64 ] For example, the hippocampus continues to develop after birth and is a structure that is affected by childhood maltreatment. [ 64 ]
It is hypothesized in [66] that the growing structure copies the axonal development of the human brain: the earliest developing connections (axonal fibers) are common at most of the subjects, and the subsequently developing connections have larger and larger variance, because their variances are accumulated in the process of axonal development.
The first stage of development runs from birth to 18 months and thus covers the infancy period. The conflict which Erikson identified during this time was trust vs mistrust. During this vulnerable point in the child's life, they are faced with uncertainties in the world and are therefore reliant on their caregiver.
The amount of time required to generate all the neurons of the CNS varies widely across mammals, and brain neurogenesis is not always complete by the time of birth. [3] For example, mice undergo cortical neurogenesis from about embryonic day (post-conceptional day) (E)11 to E17, and are born at about E19.5. [9]
Bmp-7 can be detected in the ventricular zone and is secreted into cerebrospinal fluid (CSF). The CSF is an area to promote neurogenesis and it is believed that the synergy between Bmp-7 and other regulators promote cell division along with homeostasis. [12] Other bone morphogenetic proteins are also known to impact corticogenesis in the mouse ...
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Synaptic pruning, a phase in the development of the nervous system, is the process of synapse elimination that occurs between early childhood and the onset of puberty in many mammals, including humans. [1] Pruning starts near the time of birth and continues into the late-20s. [2]