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There may also be multiple nodules. One or more lung nodules can be an incidental finding found in up to 0.2% of chest X-rays [3] and around 1% of CT scans. [4] The nodule most commonly represents a benign tumor such as a granuloma or hamartoma, but in around 20% of cases it represents a malignant cancer, [4] especially in older adults and ...
In 1996, results were published of a study of 1369 subjects screened in Japan that revealed that 73% of lung cancers that were missed by chest x-ray were detectable by CT scan. [19] Among the earliest United States-based clinical trials was the Early Lung Cancer Action Project (ELCAP), which published its results in 1999. [20]
The diagnosis of DPB requires analysis of the lungs and bronchiolar tissues, which can require a lung biopsy, or the more preferred high resolution computed tomography (HRCT) scan of the lungs. [7] The diagnostic criteria include severe inflammation in all layers of the respiratory bronchioles and lung tissue lesions that appear as nodules ...
Lung cancer can often appear as a solitary pulmonary nodule on a chest radiograph or CT scan. In lung cancer screening studies as many as 30% of those screened have a lung nodule, the majority of which turn out to be benign. [15]
Pulmonary tuberculomas are among the most common benign nodules, with 5%-24% of all resected nodules being of tuberculous origin. [21] In areas of lower prevalence, such as the United States, they are most commonly seen in the setting of an acquired immunodeficiency . [ 23 ]
Pneumonia can lead to the development of a lung abscess, [4] which is a pus-containing necrotic lesion of the lung parenchyma (lung tissue). [5] On CT scan of the chest, a lung abscess appears as an intermediate- or thick-walled cavity with or without an air-fluid level (a flat line separating the air in the cavity from the fluid). [4]
For lung nodules, air bronchograms used to be associated with infectious causes of consolidation and, therefore to be benign. However, in the setting of a lung nodule, an air bronchogram is actually more frequent in malignant than in benign nodules. [1] [4] studied the tumour-bronchus relationship and described five types: [1]
The differential for diffuse shadowing is very broad and can defeat even the most experienced radiologist. It is seldom possible to reach a diagnosis on the basis of the chest radiograph alone: high-resolution CT of the chest is usually required and sometimes a lung biopsy. The following features should be noted:
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