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  2. Candesartan - Wikipedia

    en.wikipedia.org/wiki/Candesartan

    Candesartan is marketed as the cyclohexyl 1-hydroxy ethyl carbonate (cilexetil) ester, known as candesartan cilexetil. Candesartan cilexetil is metabolised completely by esterases in the intestinal wall during absorption to the active candesartan moiety. In the first step of the cascading pro-drug mechanism, the carbonate group is hydrolyzed ...

  3. ATC code C09 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_C09

    ATC code C09 Agents acting on the renin–angiotensin system is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.

  4. Angiotensin II receptor blocker - Wikipedia

    en.wikipedia.org/wiki/Angiotensin_II_receptor...

    This class of drugs is usually well tolerated. Common adverse drug reactions (ADRs) include: dizziness, headache, and/or hyperkalemia.Infrequent ADRs associated with therapy include: first dose orthostatic hypotension, rash, diarrhea, dyspepsia, abnormal liver function, muscle cramp, myalgia, back pain, insomnia, decreased hemoglobin levels, renal impairment, pharyngitis, and/or nasal ...

  5. The twenty drugs to be made class A by the government - AOL

    www.aol.com/twenty-drugs-made-class-government...

    Twenty dangerous opioids and drugs will be banned in a new crackdown announced by the Home Office.. The ban will see 15 new dangerous synthetic opioids and five other drugs become Class A drugs ...

  6. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    Candesartan cilexetil (TCV 116) is a benzimidazole which was developed at Takeda and is an ester carbonate prodrug. In vivo, it is rapidly converted to the much more potent corresponding 7-carboxylic acid, candesartan. In the interaction of candesartan with AT 1 receptor the carboxyl group of the benzimidazole ring plays an important role ...

  7. Drug class - Wikipedia

    en.wikipedia.org/wiki/Drug_class

    A drug class is a group of medications and other compounds that share similar chemical structures, act through the same mechanism of action (i.e., binding to the same biological target), have similar modes of action, and/or are used to treat similar diseases.

  8. Cardiovascular agents - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_agents

    Cardiovascular agents are drugs used to treat diseases associated with the heart or blood vessels. These medications are available for purchase only with a physician’s prescription . They include, but are not limited to, drugs that target hypertension ( antihypertensives ), hyperlipidemia ( antihyperlipidemics ) and blood clotting (blood ...

  9. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs).

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