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Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
An equianalgesic chart is a conversion chart that lists equivalent doses of ... 10 mg ~25%: 2–4 3:1 30 ... and 0.160 mg/kg (dissociative effects) Buprenorphine
Paracetamol's bioavailability is dose-dependent: it increases from 63 % for 500 mg dose to 89 % for 1000 mg dose. [6] Its plasma terminal elimination half-life is 1.9–2.5 hours, [ 6 ] and volume of distribution is roughly 50 L. [ 132 ] Protein binding is negligible, except under the conditions of overdose, when it may reach 15–21 %. [ 6 ]
A Clarinase Repetab tablet contains 5 mg loratadine in the tablet coating and 120 mg pseudoephedrine sulfate equally distributed between the tablet coating and the barrier-coated core. The two active components in the coating are quickly liberated; release of pseudoephedrine in the core is delayed for several hours.
[20] [74] Oral acetylcysteine is given as a 140 mg/kg loading dose followed by 70 mg/kg every four hours for 17 more doses, and if the patient vomits within 1 hour of dose, the dose must be repeated. [ 75 ] [ 76 ] Oral acetylcysteine may be poorly tolerated due to its unpleasant taste, odor, and its tendency to cause nausea and vomiting. [ 72 ]
Periactin (cyproheptadine) 4 mg tablets Cyproheptadine's 3D molecular structure represented as space-filling model Cyproheptadine is used to treat allergic reactions (specifically hay fever ). [ 8 ] There is evidence supporting its use for allergies, but second generation antihistamines such as ketotifen and loratadine have shown equal results ...
The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.
[25] [26] The smaller the K d value, the greater the binding affinity of the ligand for its target. In addition to acting as an inverse agonist at the H 1 receptor, chlorphenamine has been found to act as a serotonin reuptake inhibitor (K d = 15.2 nM for the serotonin transporter ).
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