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Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
In general, proton pump inhibitors are well tolerated, and the incidence of short-term adverse effects is relatively low. The range and occurrence of adverse effects are similar for all of the PPIs, though they have been reported more frequently with omeprazole. This may be due to its longer availability and, hence, clinical experience.
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
For the drugs administered by oral and dermal route, the units of threshold dose are mg/kg body-weight/day (dose of the drug in mg per body weight in kg per day) or ppm (parts per million), while the threshold dose of drugs by inhalation delivery has the unit of mg/L 6h/day (amount of drug in mg in 1L of air, for 6 hours per day).
the dose at which toxicity occurs in 50% of cases. LD Lethal Dose the dose at which death occurs in 50% of cases. [6]: 73 [7] [8] TI Therapeutic Index a quantitative measurement of the relative safety of a drug by comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect [1]
The IMO regulation is mostly used and sets salt levels to a maximum of 50 mg/m 2 soluble salts measured as sodium chloride. These measurements are done by means of a Bresle test . Salinization (increasing salinity, aka freshwater salinization syndrome ) and subsequent increased metal leaching is an ongoing problem throughout North America and ...
Salt poisoning is an intoxication resulting from the excessive intake of sodium (usually as sodium chloride) either in solid form or in solution (saline water, including brine, brackish water, or seawater). Salt poisoning sufficient to produce severe symptoms is rare, and lethal salt poisoning is possible but even rarer.
This page provides supplementary chemical data on sodium chloride. Material safety data sheet The handling of this chemical may incur notable safety precautions ...
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