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  2. Fixed allele - Wikipedia

    en.wikipedia.org/wiki/Fixed_allele

    In contrast, the populations depicted in the latter frames exhibit fixed alleles for "color" black, red and purple respectively. A population of a hypothetical species can be conceived to exemplify the concept of fixed alleles. If an allele is fixed in the population, then all organisms can have only that allele for the gene in question.

  3. Loss of heterozygosity - Wikipedia

    en.wikipedia.org/wiki/Loss_of_heterozygosity

    The remaining copy of the tumor suppressor gene can be inactivated by a point mutation or via other mechanisms, resulting in a loss of heterozygosity event, and leaving no tumor suppressor gene to protect the body. Loss of heterozygosity does not imply a homozygous state (which would require the presence of two identical alleles in the cell).

  4. Soft selective sweep - Wikipedia

    en.wikipedia.org/wiki/Soft_selective_sweep

    The main difference between soft and hard selective sweeps lies in the expected number of different haplotypes carrying the beneficial mutation or mutations, and therefore in the expected number of haplotypes that hitchhike to considerable frequency during the selective sweep, and which remain in the population at the time of fixation.

  5. Genetic drift - Wikipedia

    en.wikipedia.org/wiki/Genetic_drift

    In these simulations, alleles drift to loss or fixation (frequency of 0.0 or 1.0) only in the smallest population. Assuming genetic drift is the only evolutionary force acting on an allele, after t generations in many replicated populations, starting with allele frequencies of p and q , the variance in allele frequency across those populations is

  6. Gene flow - Wikipedia

    en.wikipedia.org/wiki/Gene_flow

    Gene flow is the transfer of alleles from one population to another population through immigration of individuals. In population genetics, gene flow (also known as migration and allele flow) is the transfer of genetic material from one population to another. If the rate of gene flow is high enough, then two populations will have equivalent ...

  7. Neutral theory of molecular evolution - Wikipedia

    en.wikipedia.org/wiki/Neutral_theory_of...

    According to ISM, selectively neutral mutations appear at rate in each of the copies of a gene, and fix with probability / (). Because any of the 2 N {\displaystyle 2N} genes have the ability to become fixed in a population, 1 / 2 N {\displaystyle 1/2N} is equal to μ {\displaystyle \mu } , resulting in the rate of evolutionary rate equation:

  8. Hardy–Weinberg principle - Wikipedia

    en.wikipedia.org/wiki/Hardy–Weinberg_principle

    There is 1 degree of freedom (degrees of freedom for test for Hardy–Weinberg proportions are # genotypes − # alleles). The 5% significance level for 1 degree of freedom is 3.84, and since the χ 2 value is less than this, the null hypothesis that the population is in Hardy–Weinberg frequencies is not rejected.

  9. Genetic erosion - Wikipedia

    en.wikipedia.org/wiki/Genetic_erosion

    Genetic erosion in agricultural and livestock is the loss of biological genetic diversity – including the loss of individual genes, and the loss of particular recombinants of genes (or gene complexes) – such as those manifested in locally adapted landraces of domesticated animals or plants that have become adapted to the natural environment in which they originated.