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  2. Trial master file - Wikipedia

    en.wikipedia.org/wiki/Trial_master_file

    In a clinical trial involving human subjects, a set of content known as a trial master file (TMF) must be produced in accordance with applicable international and local regulations. TMFs are a collection of documents and other artifacts which "individually and collectively permit evaluation of the conduct of a trial and the quality of the data ...

  3. National Institute for Health and Care Excellence - Wikipedia

    en.wikipedia.org/wiki/National_Institute_for...

    The Guideline Development Group then finalises the recommendations and the National Collaboration Centre produces the final guideline. This is submitted to NICE to formally approve the guideline and issue the guidance to the NHS. [citation needed] To date NICE has produced more than 200 different guidelines. [28]

  4. Catheter-associated urinary tract infection - Wikipedia

    en.wikipedia.org/wiki/Catheter-associated...

    Although catheter use should be minimized in all patients, particularly those at higher risk of CAUTI and mortality (e.g. the elderly or those with impaired immunity), [2] a meta analysis suggests there is insufficient evidence to determine the value of different policies for replacing long term urinary catheters on patient outcomes. [3]

  5. Clinical study design - Wikipedia

    en.wikipedia.org/wiki/Clinical_study_design

    Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...

  6. National Institute for Health and Care Research - Wikipedia

    en.wikipedia.org/wiki/National_Institute_for...

    The NIHR (originally named National Institute for Health Research) was created in April 2006 under the government's health research strategy, Best Research for Best Health. [7] This strategy outlined the direction that NIHR research and development should take. Its predecessor was the NHS Research & Development programme which was established ...

  7. Nurses' Health Study - Wikipedia

    en.wikipedia.org/wiki/Nurses'_Health_Study

    This was a double-blind trial following an experimental group of women who were given replacement therapy pills and a control group following the same procedure with placebos. [48] Findings from the study displayed a direct relationship between therapy and risk for heart disease, as opposed to the previously stated benefits. [ 49 ]

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  9. Intermittent catheterisation - Wikipedia

    en.wikipedia.org/wiki/Intermittent_catheterisation

    Intermittent catheters come in a variety of designs and differ depending on the user's genitals, with a catheter for a penis being longer and a catheter for a vulva being shorter. The catheter is inserted into the urethra by the patient or a carer and can either be directed down a toilet or, if measurement of volume is required, into a ...