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Nerve compression syndrome, or compression neuropathy, or nerve entrapment syndrome, is a medical condition caused by chronic, direct pressure on a peripheral nerve. [1] It is known colloquially as a trapped nerve , though this may also refer to nerve root compression (by a herniated disc , for example).
Denervation can occur as a consequence of nerve injury. The three primary categories of nerve injury are neurapraxia, axonotmesis, and neurotmesis, each corresponding to varying degrees of damage and potential for recovery. In cases of nerve injury, the brain demonstrates an impressive ability to rewire or reorganize its neuronal circuitry ...
Peripheral neuropathy, often shortened to neuropathy, refers to damage or disease affecting the nerves. [1] Damage to nerves may impair sensation, movement, gland function, and/or organ function depending on which nerve fibers are affected. Neuropathies affecting motor, sensory, or autonomic nerve fibers result in different symptoms. More than ...
This type of nerve damage may cause paralysis of the motor, sensory, and autonomic functions, and is mainly seen in crush injury. [2] If the force creating the nerve damage is removed in a timely fashion, the axon may regenerate, leading to recovery. Electrically, the nerve shows rapid and complete degeneration, with loss of voluntary motor units.
An energy deficiency in Schwann cells would account for the disappearance of myelin on peripheral nerves, which may result in damage to axons or loss of nerve function altogether. In peripheral nerves, oxidative enzyme activity is most concentrated around the nodes of Ranvier, making these locations most vulnerable to cofactor deprivation ...
The damage to nerves supplying specific muscles may cause muscle twitching (fasciculations) in addition to the weakness. It is sometimes associated with weight loss. [2] Diabetes most commonly causes damage to the long nerves that supply the feet and lower legs, causing numbness, tingling and pain (diabetic polyneuropathy). Although these ...
Tissue injury may contribute to positive and/or negative symptoms, which can be attributed to the loss of nerve function and the hyperexcitability of nerve tissue. [ 4 ] [ 2 ] Additionally, nerve fibers may be differently affected by compression/ischema depending on their size, location and topography. [ 2 ]
Meralgia paresthetica or meralgia paraesthetica is pain or abnormal sensations in the outer thigh not caused by injury to the thigh, but by injury to a nerve which provides sensation to the lateral thigh. Meralgia paresthetica is a specific instance of nerve entrapment. [5] The nerve involved is the lateral femoral cutaneous nerve (LFCN).
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